Set in Rome, it is a spin-off of the series Distretto di Polizia, which aired on the same network from 2000 to 2012, reprising the character of Roberto Ardenzi, played by the protagonist Giorgio Tirabassi.
Promoted to Chief of the Mobile Squad, Deputy Police Commissioner Roberto Ardenzi was assigned to the Mafia Capitale operation, a corruption ring allegedly involving politicians, businessmen, and fixers.