Shaun Murphy, a young surgeon with autism and savant syndrome, relocates from a quiet country life to join a prestigious hospital's surgical unit. Unable to personally connect with those around him, Shaun uses his extraordinary medical gifts to save lives and challenge the skepticism of his colleagues.
Shaun and Lea get off to a bumpy start as new parents, while at work Shaun tries to navigate a problematic with one of the new residents he has to supervise: another doctor with Autism Spectrum DIsorder who idolizes him but also seems to "push all his buttons" by their very nature. Life hasn't run out of curveballs for Dr. Glassman, either, and it seems determined to force him to relive one of the hardest lessons he's yet refused to learn. Not all is bleak, though, as Drs. Park and Reznick take stock of their relationship and a chance reunion between Drs. Kalu and former team member Dr. Claire Brown soon has them entangled again as though no time had passed.