Asia is a pediatrician who is in charge of treating the children of Phanom Naka who are experiencing symptoms of a strange snake-related illness. There she ends up meeting Anantachai, the Naga King, and together they will experience various dangerous situations while trying to help the children of the village. Anantachai will go through several difficulties to get Asia to fall in love with him, and then free him from the curse that was once placed by Anachalee.
An epidemic of an unknown disease that gives children in Phanom Nakha strange snake-like scales leads Dr. Benedict to research the phenomenon. Asia, a medical illustrator, is chosen to help him with this. Along the way, the two meet Phumkhaobin, a lively but mysterious man and younger brother to Asia's friend Pheka. When joining the research, Asia couldn't have imagined that she would not only meet mysterious Phumkhaobin but also become involved in the mysterious legend of a village where people worship serpents.